Microwave assisted green synthesis of novel spiro isoxazolidine derivatives with α-chloro nitrones

Abstract

525-530Microwave assisted 1,3-dipolar cycloaddition reaction of -chloro nitrones to novel -N-methyl and -N-phenylfuran derivative affords exclusively single regioselective 5-spiro isoxazolidines while the same reaction with -methylene--butyrolactone affords two diastereomeric 5-spiro isoxazolidines with high selectivity