Decipic acid and 12-acetyl apetalic acid from <i style="">Calophyllum decipiens</i>. Wight

Abstract

393-397Triterpenes, stigmasterol, thwaitesii xanthone, apetalic acid, two new chromanones, decipic acid and 12-acetyl apetalic acid are isolated for the first time from the ethyl acetate extract of the bark of Calophyllum decipiens, Guttiferae. Structures are elucidated by spectral studies. Apetalic acid shows appreciable amount of radical scavenging activity on comparison with trolox (standard) using DPPH free radical. It also shows antibacterial activity against Mycobacterium tuberculosis H37Rv at 100 μg/mL using anti-TB drug rifampicin at 0.5 μg/mL