1542-1546Gossypin-a potential lead from nature is isolated and a series of its
derivatives (SGGOS 1-9) were synthesized
and characterized by IR, 1H NMR, mass spectral and elemental
analyses. The in vitro cytotoxic
activity on HT29 and HeLa cell lines, and in
vivo anti-inflammatory activities of the compounds were evaluated. The
synthesized variants have shown good anticancer and anti-inflammatory
activities compared to gossypin