1487-1493Protein-based polymers exhibit elasticity
and plasticity in accordance with the nature of the repeating sequence. Analogs
of parent plastic sequence AVGVP are synthesized, polymerized and characterized
in their solid state. The thermal behaviour of these polymers have been studied
by differential scanning calorimetry. Phe-containing and Ile-containing
polypentapeptides, poly(XVGVP) where X = F (Phe), I (Ile), exhibits both
melting and decomposition transitions in contrast to the decomposition alone
for parent poly(AVGVP). And also incorporation of FVGVP or IVGVP into AVGVP in
equal molar ratios, described as poly[(AVGVP),(XVGVP)] where X = F, I induces
the polymer to exhibit both melting and decomposition and shifted the values
relatively to higher temperatures due to their thermal stability. Further, the
appearance of clear exothermic crystalline transition at 251ºC, before melting
at 328ºC, for poly(IVGVP), contributes towards a typical behaviour of
thermoplasticity. Secondary structure in trifluoroethanol for all the polymers
shows, well behaved -helix as evident from the circular dichroism studies, in
association with a significant amount of random structure contributes to
extended stability