One pot synthesis of 3-acetoacetyl-5-oxo-5<i style="">H</i>-[1] benzopyrano [3,2-<i style="">e</i>]pyridin-2-one from triacetic acid lactone

Abstract

2341-2345The nucleophilic character of triacetic acid lactone has been exploited here in the Michael condensation reaction involving 2-amino-3-formylchromone as the starting material. The reaction, as visualized, afforded yellow crystalline product 4. The compound has been characterized on the basis of spectral data and evaluated for antimicrobial activit