A facile synthesis of 2-((5<i style="">R</i>)-2-oxo-5-oxazolidinyl)methyl)-1<i style="">H</i>-isoindole-1,3(2<i style="">H</i>)-dione

Abstract

1264-1268Synthesis of enantiomerically pure 2-((5R)-2-oxo-5-oxazolidinyl) methyl)-1H-isoindole-1,3(2H)-dione, a key precursor in the preparation of oxazolidinone class of antibacterial agents starting from (S)-epichlorohydrin has been achieved