Reaction of 3-aminocyclohex-2-en-1-ones with arylidenemalononitriles: Synthesis, characterization and antimicrobial activity of some new quinoline bearing pyrazole nucleus

Abstract

1170-1173A new series of quinoline bearing pyrazole nucleus D1-36 have been prepared in one pot by condensing various arylidenemalononitriles A1-3 and 3-aminocyclohex-2-en-1-ones B1-12 in alcohol and in the presence of catalytic amount of piperidine. All the compounds have been characterized by their percentage yield, melting point, elemental analysis, 1H NMR and 13C NMR spectra and IR spectra. These compounds have been screened for their antimicrobial activities.</i