The effects of defects and building directions in additive manufactured AlSi10Mg on its high-cycle fatigue and very-high-cycle fatigue performance are studied based on crystal plasticity finite element (CPFE). Among the three models provided in this work, the results of model 2 (N-p2) are in good agreement with the experimental ones. It is found the fatigue life of the sample with defects are much lower than that without defects. 0 degrees specimens have a better fatigue performance than 90 degrees ones. This work is beneficial in determining the fatigue lifetime and helps to improve the fatigue behavior of AlSi10Mg
