The purpose of this studies to examine the effect of music therapy on decreased anxiety levels and changes in vital signs in patients with mechanical ventilation. The sample of the journal reviews are the patients with mechanical ventilation in the intensive care unit. They are divided into intervention groups and control groups. The data collection is done by giving treatment of natural music instrument with music player and headset. Then the data was taken before and after treatment with anxiety measurement using Spielberger State-Trait Anxiety Inventory, VAS (visual analog scale), and measurement of vital signs of blood pressure observation, MAP (mean arterial pressure), pulse, respiratory rate (RR), oxygen saturation (SpO2). T-test data analysis technique is used to compare mean pre and post treatment in one group, test of difference between groups using chi square test. While Mann-Whitney test, multivariate analysis of variance
(MANOVA) are used to adjust research data’s scale. All of the journal reviews showed the results that client's anxiety level decreased after giving the music therapy intervention. Vital signs showed statistically
significant differences between treatment group and control group where vital signs were more stable in the
treatment group than in the control group
