The Dead Donor Rule holds that removing organs from a living human being without their
consent is wrongful killing. The rule still prevails in most countries, and I assume it without
argument in order to pose the question: is it possible to have a metaphysically correct,
clinically relevant analysis of human death that makes organ donation possible? I argue that
the two dominant criteria of death, brain death and circulatory death, are both empirically and
metaphysically inadequate as definitions of human death, and therefore of no epistemic value
in themselves. I first set out a neo-Aristotelian theory of death as separation of soul
(understood as organising principle) and body, which is then fleshed out as loss of organismic
integrity. The brain and circulatory criteria are shown to have severe weaknesses as
physiological manifestations of loss of integrity. Given the mismatch between what death is
metaphysically speaking, and the dominant criteria accepted by clinicians and philosophers, it
turns out that only actual bodily decomposition is a sure sign of death. In this I differ from
Alan Shewmon, whose important work I discuss in detail