Functional Group Selective Ion-molecule Reactions

Abstract

The mechanistic details and potential applications of ion-molecule reactions were studied. Gas phase ion-molecule reactions was placed at the center of attention in mass spectrometry. The combination of conventional and new ionization and multiple-stage mass spectrometry techniques provide access for mass spectrometrists to a world of gaseous ions, reaction environments, and ion characterization methods. Functional group selective ion-molecule reactions will certainly found increasing applications in a variety of fields.1314Staley, R.H., Corderman, R.R., Foster, M.S., Beauchamp, J.L., (1974) J. Am. Chem. Soc., 96, p. 1260Moraes, L.A.B., Eberlin, M.N., (2000) Chem. Eur. J., 6, p. 897Kenttamaa, H.I., Cooks, R.G., (1989) J. Am. Chem. Soc., 111, p. 4122Moraes, L.A.B., Eberlin, M.N., (2002) J. Mass Spectrom., 37, p. 162Eberlin, M.N., Cooks, R.G., (1993) J. Am. Chem. Soc., 115, p. 9226Meurer, E.C., Eberlin, M.N., (2001) Int. J. Mass Spectrom., 210-211, p. 469Carvalho, M., Gozzo, F.C., Mendes, M.A., Sparrapan, R., Kascheres, C., Eberlin, M.N., (1998) Chem. Eur. J., 4, p. 1161Moraes, L.A.B., Eberlin, M.N., (1996) J. Org. Chem., 61, p. 8726Moraes, L.A.B., Gozzo, F.C., Eberlin, M.N., (1997) J. Org. Chem., 62, p. 5096H. Chen, X. Zheng, R. G. Cooks, unpublished resultsEberlin, M.N., Cooks, R.G., (1993) Org. Mass Spectrom., 28, p. 679Thompson, R.S., Guler, L.P., Nelson, E.D., Yu, Y.-Q., Kenttamaa, H.L., J. Org. Chem., , in pressStirk, K.M., Orlowski, J.C., Leeck, D.T., Kenttamaa, H.I., (1992) J. Am. Chem. Soc., 114, p. 8604Ramos, L.E., Cardoso, A.M., Ferrer Correia, A.J., Nibbering, N.M.M., (2000) Int. J. Mass Spectrom., 203, p. 101Kempen, E.C., Brodbelt, J., (1997) J. Mass Spectrom., 32, p. 846O'Hair, R.A.J., Reid, G.E., (2000) J. Am. Soc. Mass Spectrom., 111, p. 244Reid, G.E., Tichy, S.E., Pérez, J., O'Hair, R.A.J., Simpson, R.J., Kenttamaa, H.I., (2001) J. Am. Chem. Soc., 123, p. 1184Cooks, R.G., (2002) 50th Annual Conference on Mass Spectrometry and Allied Topics, , Monday Plenary Lecture, Orlando, Jun