Skeletal Muscles With Antagonistic Muscular Actions: Morphological, Contractile And Metabolic Characteristics [músculo Esquelético Con Acción Muscular Antogonista:características Metabólicas, Contratiles Y Morfológicas]

Abstract

The muscles can perform the same function in a specific segment (muscles of fast and slow contraction), and at the same time be antagonistic in relation to muscular action (flexors or extensors). The present research aimed to study the morphology, frequency and metabolism of fiber types and the contractile characteristics of extensor and flexors muscles of rabbit. We studied muscles anterior tibialis (AT), flexor digitorum supeficialis (FDS), extensor digitorum longus (EDL) and posterior tibialis (PT). The muscles were submitted to the techniques HE, NADH-TR and myofibrillar ATPase. In EDL and PT extensor muscles, the frequencies of red (SO + FOG) and white fibers (FG) were 68.77% and 31.23% versus 58.87% and 41.13%, respectively. In the AT and FDS flexor muscles, these frequencies were 75.14% and 24.86% versus 73.89% and 26.11%, respectively. In extensor muscles, the percentage of slow contraction fibers was 8.05% in EDL and 9.74% in PT, and in fast contraction, 91.95% in EDL and 90.26% in PT. In flexors, the slow contraction frequencies were 12.35% in AT and 8.17% in FDS, and in fast contraction, 87.65% and 91.83%, respectively. Skeletal muscles with antagonistic muscular actions (flexors and extensors) the morphological, contractile and metabolic characteristics are identical.27411731178Ariano, M.A., Armstrong, R.B., Edgerton, V.R., Hind limb muscle fiber populations of five mammals (1973) J. Histochem. Cytochem, 21, pp. 51-66Ashley, A., Sutherland, H., Lanmüller, H., Russold, M.F., Unger, E., Bijak, M., Mayr, W., Jarvis, J.C., Atrophy, but not necrosis, in rabbit skeletal muscle denervated for periods up to one year (2007) Am. J. Physiol. Cell. Physiol, 292, pp. 440-451Berquó, E.S., Souza, J.M.P., Gotlied, S.L.D., Souza, J.F.P., (1981) Bioestatística, p. 350. , São Paulo, Pedagógica e Universitária (EDUSP)Biral, D., Kern, H., Adami, N., Boncompagni, S., Protasi, F., Carraro, U., Atrophy-resistant fibers in permanent peripheral denervation of human skeletal muscle (2008) Neurol. Res, 30 (2), pp. 137-144Dubowitz, V., Brooke, M.H., (1972) Muscle Biopsy: A Modern Approach, p. 432. , Philadelphia, SaundersFlück, M., Hoppeler, H., Molecular basis of skeletal muscle plasticity from gene to form and function (2003) Rev. Physiol. Biochem. Pharmacol, 146, pp. 156-216Galler, S., Wang, B.G., Kawai, M., Elementary steps of the cross-bridge cycle in fast-twitch fiber types from rabbit skeletal muscles (2005) Biophysical J, 89, pp. 3248-3260Goldspink, G., Changes in muscle and phenotype and the expression of autocrine and systemic growth factors by muscle in response to stretch and overload (1999) J. Anat, 19, pp. 323-334Gollnick, P.D., Músculo-esquelético: Estrutura e função (2003) Fisiologia Do Exercício. Energia, Nutrição E Desempenho Humano, p. 1113. , In: McArdley, W. D.Katch, F. I. & Katch, V. L, 5a ed. Rio de Janeiro, Guanabara KooganGueguen, N., Lefaucheur, L., Fillaut, M., Herpin, P., Muscle fiber contractile type influences the regulation of mitochondrial function (2005) Mol. Cell. Biochem, 276 (1-2), pp. 15-20Hämäläinen, N., Pette, D., The histochemical profiles of fast fiber types IIB, IID, and IIA in skeletal muscles of mouse, rat, and rabbit (1993) J. Histochem. Cytochem, 41, pp. 733-743Hebel, R., Stromberg, M.W., (1976) Anatomy of The Laboratory Rat, p. 173. , Baltimore, William & Wilkins CompanyKarlsson, J., Jabobs, I., Músculo-esquelético: Estrutura e função (2003) Fisiologia Do Exercício. Energia, Nutrição E Desempenho Humano, p. 1113. , In: McArdley, W. D.Katch, F. I. & Katch, V. L, 5a ed., Rio de Janeiro, Guanabara KooganLarsson, L., Edström, L., Lindegren, B., Gorza, L., Schiaffino, S., MHC composition and enzyme-histochemical and physiological properties of a novel fast-twitch motor unit type (1991) Am. J. Physiol, 261, pp. 93-101McMannus, J.F.A., Mowry, R.W., Histochemical studies on developing mast cells (1964) Anat. Rec, 150, pp. 265-269McKoy, G., Léger, M.E., Bacou, F., Goldspink, G., Diferential expression of myosin heavy chain mRNA and protein isoforms in four functionally, diverse rabbit skeletal muscles during pre-and postnatal development (1998) Dev. Dyn, 211, pp. 81-100Pai-Silva, M.D., Ueda, A.K., Resende, L.A., Pai, V.D., Alves, A., Faleiros, A.T., Morphological aspects of rabbit masseter muscle after cervical sympathectomy (2001) Int. J. Exp. Pathol, 82 (2), pp. 123-128Peter, J.B., Barnard, R.J., Edgerton, V.R., Gilliespie, C.A., Stempel, K.E., Methabolic profiles of three fiber types of skeletal muscle in guinea pigs and rabbits (1972) Biochemistry, 11, pp. 2627-2637Prado, L.G., Makarendo, I., Andresen, C., Krüger, M., Optiz, C.A., Linke, W.A., Isoform diversity of giant proteins in relation to passive and active contractile properties of rabbit skeletal muscles (2005) J. Gen. Physiol, 126 (5), pp. 461-48