Effects Of Long-term Creatine Monohydrate Supplementation On Anaerobic Performance Of Trained Young Adults [efeitos Da Suplementação Prolongada De Creatina Mono-hidratada Sobre O Desempenho Anaeróbio De Adultos Jovens Treinados]

Abstract

The objective of the present study was to investigate the impact of eight weeks of creatine monohydrate (Crm) supplementation on the anaerobic performance of young trained adults. Twenty-six healthy male physical education students were randomly divided in creatine group (CrG, n = 13; 22.5 ± 2.7 years; 74.9 ± 6.8 kg; 178.5 ± 4.8 cm) and placebo group (PlG, n = 13; 22.9 ± 3.2 years; 71.9 ± 11.3 kg; 178.6 ± 4.0 cm). The subjects received in a double-blind system a Crm or placebo-maltodextrin dose (20 g.d-1 for 5 days and 3 g.d-1 for 51 subsequent days). Both groups had their eating habits and levels of physical fitness previously controlled. The Wingate anaerobic test (WT) was used to evaluate the anaerobic performance before and after the ingestion period of Crm or placebo. The performance indexes assessed were: relative peak power (RPP), relative mean power (RMP), relative total work (RTW) and index of fatigue (IF). ANOVA followed by Tukey post hoc test were used when P<0.05 for statistical treatment. No significant difference in RPP, RMP, RTW or IF was observed after the period of supplementation of Crm (P>0.05). The results of the present study suggest that Crm supplementation does not seem to be an efficient ergogenic resource in high-intensity and short-duration efforts involving a single set.163186190Mesa, J.L., Ruiz, J.R., Gonzalez-Gross, M.M., Gutierrez-Sainz, A., Garzon, M.J.C., Oral creatine supplementation and skeletal muscle metabolism in physical exercise (2002) Sports Med, 32, pp. 903-944Branch, J.D., Effect of creatine supplementation on body composition and performance: A meta-analysis (2003) Int J Sport Nutr Exerc Metab, 13, pp. 198-226Persky, A.M., Rawson, E.S., Safety of creatine supplementation (2007) Subcell Biochem, 46, pp. 275-289Brudnak, M.A., Creatine: Are the benefits worth the risk? (2004) Toxicol Lett, 150, pp. 123-130Pischel, I., Gastner, T., Creatine: Its chemical synthesis, chemistry, and legal status (2007) Subcell Biochem, 46, pp. 291-307Hultman, E., Greenhaff, P.L., Ren, J.M., Soderlund, K., Energy metabolism and fatigue during intense muscle contraction (1991) Biochem Soc Trans, 19, pp. 347-353Allen, D.G., Lamb, G.D., Westerblad, H., Skeletal muscle fatigue: Cellular mechanisms (2008) Physiol Rev, 88, pp. 287-332Balsom, P.D., Söderlund, K., Sjödin, B., Ekblom, B., Skeletal muscle metabolism during short duration high-intensity exercise: Influence of creatine supplementation (1995) Acta Physiol Scand, 154, pp. 303-310Cooke, C.B., Theodorou, A., King, R.F.G.J., Gibbon, W., Frain, M., The effects of a creatine maintenance dosage on muscle metabolites and anaerobic performance (1999) Med Sci Sports Exercise, 31, pp. S354Havenetidis, K., Theodorou, A., Cooke, C.B., King, R.F.G.J., Effects of an acute Cr loading on muscle metabolites and anaerobic performance (2002) Annual Congress of The European College of Sport Science, p. 593. , Atenas, 2002. Proceedings. AtenasVandenberghe, K., van Hecke, P., van Leemputte, M., Vanstapel, F., Hespel, P., Phosphocreatine resynthesis is not affected by creatine loading (1999) Med Sci Sports Exercise, 31, pp. 236-242Bar-Or, O., The Wingate anaerobic test: An update on methodology, reliability and validity (1987) Sports Med, 4, pp. 381-394Havenetidis, K., Matsouka, O., Cooke, C.B., Theodorou, A., The use of varying creatine regimes on sprint cycling (2003) J Sports Sci Med, 2, pp. 88-97Snow, R.J., Murphy, R.M., Factors influencing creatine loading into human skeletal muscle (2003) Exercise Sport Sci Rev, 31, pp. 154-158Position stand: Progression models in resistance training for healthy adults (2002) Med Sci Sports Exerc, 34, pp. 364-380. , American College of Sports MedicineGordon, C.C., Chumlea, W.C., Roche, A.F., Stature, recumbent length, and weight (1988) Anthropometric Standardization Reference Manual, pp. 3-8. , In: Lohman TG, Roche AF, Martorell R., editors, Champaign: Human KineticsHespel, P., Op't eijnde, B., van Leemputte, M., Opposite actions of caffeine and creatine on muscle relaxation time in humans (2002) J Appl Physiol, 92, pp. 513-518Green, A.L., Simpson, E.J., Littlewood, J.J., Macdonald, I.A., Greenhaff, P.L., Carbohydrate ingestion augments creatine retention during creatine feeding in humans (1996) Acta Physiol Scand, 158, pp. 195-202Havenetidis, K., Matsouka, O., Konstadinou, V., Establishment of the highest peak anaerobic power prior to the commencement of the anaerobic Wingate test (2003) J Hum Mov Stud, 44, pp. 479-487Okano, A.H., Dodero, S.R., Coelho, C.F., Gassi, E., Altimari, L.R., Silva, C.C., Efeito da aplicação de diferentes cargas sobre o desempenho motor no teste de Wingate Rev Bras Ciên E Mov, 9, pp. 39-44. , 200Rawson, E.S., Perski, A.M., Price, T.B., Clarkson, P.M., Effects of repeated creatine supplementation on muscle, plasma, and urine creatine levels (2004) J Strength Cond Res, 18, pp. 162-167Narayanan, S., Appleton, H.D., Creatinine: A review (1980) Clin Chem, 26, pp. 1119-1126Barr, S.I., Rideout, C.A., Nutritional considerations for vegetarian athletes (2004) Nutrition, 20, pp. 696-703Odland, L.M., Macdougall, J.D., Tarnopolsky, M.A., Elorriaga, A., Borgmann, A., Effect of oral creatine supplementation on muscle [PCr] and short-term maximum power output (1997) Med Sci Sports Exercise, 29, pp. 216-219Cooke, W.H., Grandjean, P.W., Barnes, W.S., Effect of oral creatine supplementation on power output and fatigue during bicycle ergometry (1995) J Appl Physiol, 78, pp. 670-673Dawson, B., Cutler, M., Moody, A., Lawrence, S., Goodman, C., Randall, N., Effects of oral creatine loading on single and repeated maximal short sprints (1995) Aust J Sci Med Sport, 27, pp. 56-61Snow, R.J., McKenna, M.J., Selig, S.E., Kemp, J., Stathis, C.G., Zhao, S., Effect of creatine supplementation on sprint exercise performance and muscle metabolism (1998) J Appl Physiol, 84, pp. 1667-1673Ledford, A., Branch, J.D., Creatine supplementation does not increase peak power production and work capacity during repetitive wingate testing in women (1999) J Strength Cond Res, 13, pp. 394-399Earnest, C.P., Snell, P.G., Rodriguez, R., Almada, A.L., Mitchell, T.L., The effect of creatine monohydrate ingestion on anaerobic power indices, muscular strength and body composition (1995) Acta Physiol Scand, 153, pp. 207-209Casey, A., Constantin-Teodosiu, D., Howell, S., Hultman, E., Greenhaff, P.L., Creatine ingestion favorably affects performance and muscle metabolism during maximal exercise in humans (1996) Am J Physiol, 271, pp. 31-37Green, J.M., McLester, J.R., Smith, J.E., Mansfield, E.R., The effects of creatine supplementation on repeated upper- and lower-body Wingate performance (2001) J Strength Cond Res, 15, pp. 36-41Tarnopolsky, M.A., Maclennan, D.P., Creatine monohydrate supplementation enhances high-intensity exercise performance in males and females (2000) Int J Sport Nutr Exercise Metab, 10, pp. 452-463Kurosawa, Y., Hamaoka, T., Katsumura, T., Kuwamori, M., Kimura, N., Sako, T., Creatine supplementation enhances anaerobic ATP synthesis during a single 10 sec maximal handgrip exercise (2003) Mol Cell Biochem, 244, pp. 105-112Birch, R., Noble, D., Greenhaff, P.L., The influence of dietary creatine supplementation on performance during repeated bouts of maximal isokinetic cycling in man (1994) Eur J Appl Physiol Occup Physiol, 69, pp. 268-270Havenetidis, K., Cooke, C.B., King, R.F.G.J., Butterly, R., The effect of creatine supplementation on repeated 30 s cycle sprints in man (1995) J Physiol, 483, pp. S122Greenhaff, P.L., Casey, A., Short, A.H., Harris, R., Söderlund, K., Hultman, E., Influence of oral creatine supplementation on muscle orque during repeated bouts of maximal voluntary exercise in man (1993) Clin Sci, 84, pp. 565-571Harris, R.C., Söderlund, K., Hultman, E., Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation (1992) Clin Sci, 83, pp. 367-374Greenhaff, P.L., Bodin, K., Söderlund, K., Hultman, E., Effect of oral creatine supplementation on skeletal muscle phosphocreatine resynthesis (1994) Am J Physiol, 266, pp. 725-730Vandewalle, H., Peres, G., Monod, H., Standard anaerobic exercise tests (1987) Sports Med, 4, pp. 268-289Weinstein, Y., Bediz, C., Dotan, R., Falk, B., Reliability of peak-lactate, heart rate, and plasma volume following the Wingate test (1998) Med Sci Sports Exercise, 30, pp. 1456-1460Prevost, M.C., Nelson, A.G., Morris, G.S., Creatine supplementation enhances intermittent work performance (1997) Res Q Exercise Sport, 68, pp. 233-240Andrews, R., Greenhaff, P.L., Curtis, S., Perry, A., Cowley, A.J., The effect of dietary creatine supplementation on skeletal muscle metabolism in congestive heart failure (1998) Eur Heart J, 19, pp. 617-622Rieu, M., Duvallet, A., Scharapan, L., Thieulart, L., Ferry, A., Blood lactate accumulation in intermittent supramaximal exercise (1988) Eur J Appl Physiol Occup Physiol, 57, pp. 235-242Havenetidis, K., Bourdas, D., Creatine supplementation: Effects on urinary excretion and anaerobic performance (2003) J Sports Med Phys Fitness, 43, pp. 347-35

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