Tissue engineering is an interdisciplinary field that applies biological and engineering knowledge to develop replacement tissue, for example, bone tissue. Normally, scaffolds are used to provide a support for cell migration, attachment, and proliferation. However, biomimetic surface modification of scaffolds has proved to be an improvement of interaction between materials and biological tissues. These changes can induce a specific cellular response and thereby enhance the desired effects. This paper describes fabrication and coating processes of scaffolds. The coating process consist in immersed the scaffold in solutions of PLA and gelatin, followed evaporative drying in ambient temperature. For characterization were used: scanning electron microscopy (SEM), optical microscopy (OP), stereoscopy, transmission electron microscopy (TEM), X-ray microtomography (Micro-CT), X-ray diffraction (XRD) and X-ray fluorescence (XRF). The bioceramic materials used in this work showed particles size between 10 and 45 nm, and low chemical contamination. The scaffolds showed morphology with adequate porosity for tissue engineering. We suggest that the particle size used improved the process of polymer foam replication, and the coated scaffolds showed evidence of not being cytotoxic.631289294Santos, A.R., Jr., Lombello, C.B., Genari, S.C., (2012) Book Tissue Regeneration-From Basic Biology to Clinical Application, p. 512. , Chapter 16, 339-366, Edited by Prof. Jamie DaviesVogt, C.D., Xing, Q., Frost, M., Zhao, F., (2012) Biomedical Engineering Society-Advancing Human Health and Well Being, , Atlanta, Georgia, EUA(2008) Sigma Aldrich., 3 (8), pp. 1-28Li, D., Frey, M.W., Baeumner, A.J., (2006) Journal of Membrane Science, 279, pp. 354-367Mellado, P., McLlwee, H.A., Badrossamay, M.R., Goss, J.A., Mahadevan, L., Parker, K.K., (2011) Applied Physics Letters., 99, pp. 2031071-2031073Haimi, S., Suuriniemi, N., Haaparanta, A.M., Ella, V., Lindroos, B., Huhtala, H., Raty, S., Suuronen, R., (2009) Tissue Engineering Part A., 15 (7), pp. 1473-1480Dimai, H.P., Linkhart, T.A., Linkhart, S.G., Donahue, L.R., Beamer, W.G., Rosen, C.J., Farley, J.R., Baylink, D.J., (1998) Bone., 22 (3), pp. 211-216Mohamadnia, A.R., Shahbazkia, H.R., Sharifi, S., Shafaei, I., (2007) Comparative Clinical Pathology., 16 (4), pp. 265-270Rodrigues, L.R., D'Avila, M.A., Monteiro, F.J., Zavaglia, C.A.C., (2012) Materials Research., 15 (6), pp. 974-980Wu, S.C., Hsu, H.C., Hsu, S.K., Wang, W.H., Ho, W.F., (2011) Materials Characterization., 62, pp. 526-534Zhou, Z., Buchanan, F., Mitchell, C., Dunne, N., (2014) Materials Science and Engineering C., 38, pp. 1-10Franca, R., Samani, T.D., Bayade, G., Yahia, L.H., Sacher, E., (2014) Journal of Colloid and Interface Science, 420, pp. 182-188Zhu, X., Eibl, O., Berthold, C., Scheideler, L., Geis-Gerstorfer, J., (2006) Nanotechnology, 17, pp. 2711-2721Naldoni, A., Minguzzi, A., Vertova, A., Dal Santo, V., Borgesec, L., Bianchi, C.L., (2010) Journal of Materials Chemistry, 21, pp. 400-407Rodrigues, L.R., Motisuke, M., Zavaglia, C.A.C., (2009) Key Engineering Materials, 396-398, pp. 623-626Rodrigues, L.R., Motisuke, M., Zavaglia, C.A.C., Synthesis of b-TCP nanoparticles by sol-gel process (2010) 6th Latin American Congress of Artificial Organs and Biomaterials, , Gramado, Rio Grande do Sul, BrazilKalita, S.J., Bhatt, H.A., (2007) Materials Science and Engineering C., 27, pp. 837-848Motisuke, M., Carrodeguas, R.G., Zavaglia, C.A.C., (2011) Materials Research, 14 (4), pp. 493-498ASTMF1635-1
