UPAYA PENINGKATAN KELARUTAN SENYAWA MH2011 DENGAN PELARUT PROPILEN GLIKOL

Abstract

MH2011 [1-[4-hydroxynaphthalen-1-yl]-3-(4-hydroxyphenyl) urea] is a new compound that is synthesized from urea staring material urea combined with 4- amino-1-4-amino-1-naphthol and p-aminophenols. Research has been conducted to determine the solubility of compound MH2011 in solvents of water and an increase in solubility using the method cosolvent. MH2011 solubility increases 8.6 times as much on the use of cosolvent ethanol with levels of 7.0% from the total volume of the solvent used. It is less satisfying because ethanol is a common cosolvent for use, therefore try to use alternative to replace cosolvent ethanol. Alternative cosolven used are propylene glycol. On the use of rates of 7.0% propylene glycol not ethanol can replace as kosolvent, but when cosolvent is raised levels of compound solubility profile MH2011 will go up and follow the pattern of non linear