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research
Identification of metabolic pathways using pathfinding approaches: A systematic review
Authors
A Abdullah
ZA Algfoor
H Kolivand
MS Sunar
Publication date
1 January 2017
Publisher
'Oxford University Press (OUP)'
Doi
Cite
Abstract
Metabolic pathways have become increasingly available for variousmicroorganisms. Such pathways have spurred the development of a wide array of computational tools, in particular, mathematical pathfinding approaches. This article can facilitate the understanding of computational analysis ofmetabolic pathways in genomics. Moreover, stoichiometric and pathfinding approaches inmetabolic pathway analysis are discussed. Threemajor types of studies are elaborated: stoichiometric identification models, pathway-based graph analysis and pathfinding approaches in cellular metabolism. Furthermore, evaluation of the outcomes of the pathways withmathematical benchmarkingmetrics is provided. This review would lead to better comprehension ofmetabolismbehaviors in living cells, in terms of computed pathfinding approaches. © The Author 2016
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oai:generic.eprints.org:75455/...
Last time updated on 10/04/2018
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Universiti Teknologi Malaysia Institutional Repository
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Crossref
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info:doi/10.1093%2Fbfgp%2Felw0...
Last time updated on 17/09/2020