We introduce the volume that collects the papers presented at the 4th Workshop Gamma-Ray Bursts in the Afterglow Era, held in Rome on October 18-22, 2004. After a general introduction and description of theWorkshop, we briefly
review the hot topics in GRB science which were discussed during the conference and are the subject of many articles included in these proceedings. Finally, we focus on future prospects for GRB science at the beginning of the Swift era and beyond