Objective: This paper will give a clinical study on patients with severe craniocerebral injury, so as to explore the clinical effect of evidence-based nursing in the trachea incision in patients with severe craniocerebral trauma, in order to improve the effect of nursing patients with severe craniocerebral injury, and provide a reliable basis and ultimately improve the quality of life and life safety. Methods: The study group of severe craniocerebral injury patients with tracheotomy to evidence-based nursing measures; control group of severe craniocerebral injury patients with tracheotomy to routine clinical nursing measures. Observe and record the time of hospitalization, mortality and respiratory tract infection occurred in two patients, give statistical analysis, draw the conclusion. Results: The study group of severe craniocerebral trauma by clinical nursing of trachea evidence-based nursing measures for patients after incision, the incidence rate was 43.75%, the mortality rate was 12.50%, the average hospitalization time was 23.44± 7.83 days the respiratory tract infection, the incidence rate was 81.25%, the mortality rate was 37.50%, the average hospitalization time was 31.50± 9.25 days, and the P<0.05 patients with respiratory tract infection severe craniocerebral injury of trachea was significantly better than the control group only received routine nursing care measures for incision, the results of between two groups have statistical significance. Conclusion: Severe brain trauma after tracheotomy patient to prevent gas of evidence-based nursing, avoid infection of incision of evidence-based nursing, ensure unimpeded respiratory tract of evidence-based nursing, airway humidification of evidence-based nursing care, environment and equipment of evidence-based nursing in clinical nursing measures and subcutaneous bleeding, can effectively improve the clinical nursing effect, reduce the occurrence of rate and mortality in patients with respiratory tract infection, shorten hospitalized time, improve patient safety and quality of life, worthy of clinical application.目的 本文将对重型颅脑外伤患者给予临床研究，从而探讨循证护理在重型颅脑外伤气管切开患者的临床效果，为提高重型颅脑外伤患者护理效果，最终提高其生活质量与生命安全提供可靠依据。方法 研究组重型颅脑外伤气管切开患者给予循证护理措施；对照组重型颅脑外伤气管切开患者仅进行常规临床护理措施。观察并记录两组患者发生呼吸道感染情况、死亡率以及住院时间，给予统计学分析，得出结论。结果 研究组重型颅脑外伤气管切开患者经循证护理措施进行临床护理后，其呼吸道感染发生率为43.75%、死亡率为12.50%、平均住院时间为23.44±7.83天，均明显优于对照组仅进行常规护理措施进行护理的重型颅脑外伤气管切开患者呼吸道感染发生率为81.25%、死亡率为37.50%、平均住院时间为31.50±9.25天，且P <0.05, 两组患者对比结果具有统计学意义。结论 对重型颅脑外伤气管切开患者给予防止大出血及皮下积气循证护理、避免切口感染循证护理、确保呼吸道畅通循证护理、湿化气道循证护理、环境及设备循证护理等临床护理措施，能够有效提高患者临床护理效果，降低患者呼吸道感染发生率以及死亡率，明显缩短患者入院治疗时间，提高患者生活质量与生命安全，值得临床推广应用
