Objective: To explore Mediating Effect between the college students' irrational beliefs and stress susceptibility. Method: 920 students which from different type of universities were assessed with the stress susceptibility assessment scale, irrational beliefs questionnaire and self-efficacy questionnaire. Results and Conclusion: There was a close connection between pressure susceptibility and irrational belief . Whether the individual had high irrational beliefs or low irrational beliefs, maintained high self-efficacy had lower pressure of the individual susceptibility than the individuals with low self-efficacy. The individuals who holding the high pressure of irrational beliefs had lower stress susceptibility than the individuals who holding irrational beliefs, the individuals holding low irrational beliefs and high self-efficacy had the lowest stress susceptibility. Female college students stress susceptibility overall less than men, but in the case of individual holding higher unreasonable belief, the difference was not obvious.本文采用压力易感性评估量表、不合理信念问卷、自我效能感问卷,对920名来自不同类型高等院校的大学生进行了调查,以探究自我效能感在大学生不合理信念与压力易感性中的中介作用。结果与结论 压力易感性与不合理信念之间存在密切关联;无论个体是持有高不合理信念或是低不合理信念,保持着高自我效能感的个体比持有低自我效能感的个体的压力易感性更低;持有高不合理信念的个体的压力易感性要高于持有低不合理信念的个体,持有低不合理信念的同时又拥有高自我效能感的个体的压力易感性最低;女性大学生的压力易感性总体低于男性,然而在个体持有较高不合理信念的情况下,二者差异并不明显