目的 分析消毒供应中心发生锐器伤的原因,采取防护对策,有效规避锐器伤,保障工作人员职业安全。方法 采用回顾性调查法,汇总消毒供应中心2013年锐器伤数据,分析发生锐器伤的原因,制定防护对策。结果 锐器伤主要发生在器械分类、手工清洗及器械包装过程中。结论 消毒供应中心工作人员职业防护意识淡薄,操作不规范,培训和监管不到位是发生锐器伤的主要原因。Objective: To analyze the causes of sharp injury in the sterilization and supply center, take protective measures, effectively avoid sharp instrument injury, and guarantee staff safety. Methods: Adopt a retrospective survey method, summarize sharp instrument injury data of sterilization and supply center in 2013, analyze the reasons of the occurrence of sharp instrument injury, and make protective countermeasures. Results: Sharp instrument injuries occurred mainly in the device classification, manual cleaning and device packaging process. Conclusion: Poor consciousness of occupational protection of the staff in the sterilization and supply center, nonstandard operation, and lack of training and supervision in place are the main reasons of occurrence of sharp instrument injury