To improve medical students' autonomous learning, clinical thinking and problem analysis and problem solving, and clinical practice skills, TBL teaching and clinical practice and case analysis are introduced in medical genetics teaching. The students could promote autonomous learning and independent study through consulting data, group discussion, and social practice. The whole process of heuristic, participatory teaching, could fully mobilize the enthusiasm and initiative of students, making students become the subject of learning, and interaction between teachers and students, students interaction and group discussion, as one of the social practice teaching mode. In this teaching model, students get horizontal contact of knowledge, vertical infiltration, which make the basic medical knowledge and clinical medical knowledge effectively integrate, achieving good teaching effect.为提高医学生自主学习、临床思维、分析问题和解决问题及临床实践技能，将TBL教学法及临床实践和病例分析引入医学遗传学教学中，学生通过查阅资料、团队讨论、社会实践等途径自主学习、自主研究，整个教学过程中贯穿着启发式、参与式教学，充分调动了学生学习的积极性和主观能动性，让学生成为学习的主体，集师生互动、同学互动和团队讨论、社会实践为一体的教学模式。在该教学模式中，学生对所学知识进行横向联系，纵向渗透，使基础医学知识和临床医学知识有效整合，取得了良好的教学效果
