Natural slopes in clayey soils are often affected by failures which may cause the onset of landslides of the flow type travelling large distances and damaging buildings and major infrastructures. Particularly, the so-called earthflows pose challenging tasks for the individuation and forecasting of the remobilized masses; as a consequence, the mathematical modelling of the propagation stage allows enhancing the understanding of earthflows in order to obtain reliable assessments of run-out distances and displaced soil volumes. This paper deals with the reactivations of Montaguto earthflow (Southern Italy) occurred from 1998 to 2009 that are simulated, through the depth-integrated “GeoFlow-SPH” model, thanks to the availability of a detailed data-set. The achieved results provide a satisfactory agreement with the in-situ information and outline how a change of the rheology of the mobilized masses can affect the whole phenomenon