Fatigue is the one of the main contributors to problems related to structural safety of civil and marine structures. Life-cycle management (LCM) techniques considering various uncertainties can be used to predict the safe service life of fatigue sensitive structures, plan for their future inspections and support the decision making process regarding maintenance and repair actions. This paper provides a brief overview of the LCM of fatigue sensitive civil and marine structures under uncertainty. Probabilistic performance prediction, inspection scheduling and maintenance optimization for such structures are discussed
