This research is observational analytical research with a cross-secional approach. The research was conducted on industrial engineering students of Muhammadiyah University of Surakarta with a sample of 250 respondents selected using purposive sampling. Independent or exogenous variables are predisposing factors (interests, talents, passions, hobbies, knowledge, attitudes and education levels); reinforcing factors (creativity, motivation, opportunity and model (success story); enabling factors (willingness of facilities and social networks). Intervening variables are internal factors (gender and age) and external factors (social and environmental support). Dependent or endogenous variables are mental entrepreneurship. The mental grain of entrepreneurship is judged from tenacious, diligent, capable, unyielding, independent, professional and confident indicators. The data was collected using questionnaires and analyzed with path analysis