Tinjauan Artikel : Aktivitas Antidiabetes Antosianin

Abstract

Diabetes is a chronic metabolic disease which characterized by increased blood sugar levels. The prevalence of diabetes sufferers in Indonesia in 2013 was 6.9% and increased by 8.5% in 2018. Increased use of diabetes drugs has the potential to increase side effects. Some of the side effects often experienced by diabetes patients are nausea and hypoglycemia. Therefore, a new focus is needed to overcome the side effects that occur, one of which is to use traditional medicine. There have been many studies on plants that have antidiabetic activity with compounds that play an active role, namely terpenoid flavonoids and saponins. One group of flavonoid is an anthocyanin that has been widely studied for its properties, including anti-cancer and antidiabetic properties. This literature review aims to determine the effectiveness of anthocyanins as antidiabetic agents. This literature review is obtained from articles searched through the PubMed database, using the keyword "anthocyanins and antidiabetic activity". Some of the inclusion criteria were in vitro studies and primary articles with the publication year 2016-2020. From these results, 7 articles that met the criteria were determined and used as reviews. Based on the analysis, the anthocyanin compoundsfound in plants have pharmacological activity as an antidiabetic agent with several mechanis

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