It is well acknowledged that there is a strong correlation between systemic nutrition and immunological state in human. This mutual dependency can be manifested, especially, in the digestive tract. The intestine, which is the first entry organ of the nutrients, is located in the border of internal circumstance and outer one of the body. It, therefore, is furnished the highly developed immunological self-defending system. Recent studies have been clarified the impaired intestinal defense systems allow the bacterial invasion through the mucosal surface of the digestive tract, which is called " bacterial translocation (BT) ".In the clinical nutritional management, it has been often reported that enteral nutrition (EN) has much more beneficial effects, compared with parenteral nutrition (PN) through the maintaining the intestinal integrity. The data of superiority of EN were introduced in this paper in both experimental and clinical studies. On the viewpoints of these evidences, in conclusion, enteral nutrition is more adequate modality of nutritional giving as long as the intestine can be functioned
