Razi Institute for Drug Research (RIDR) of Iran University of Medical Sciences and Health Services (IUMS)
Abstract
The Suffof-e-Suzak Qawi is an unani polyherbomineral formulation and is
being used in the alternative system of medicine for its
anti-gonorrheal and diuretic activity. It is an official monograph in
national formulary of unani medicine (NFUM) and reported as
anti-gonorrheal and diuretic. The aqueous suspension of the formulation
was studied for its possible diuretic activity and its effect on
urinary sodium and potassium excretion. The results were compared with
animal groups treated with vehicle and standard drug furosemide. When
tested in healthy adult rats the formulation at a dose of 500, 750 and
1000 mg/kg has shown increase in the urinary output and urinary sodium
excretion but not any increase in the urinary potassium excretion at
all dose levels. The present study showed that, the aqueous suspension
of Suffof-e-Suzak Qawi has diuretic activity comparable with the
standard drug furosemide in producing urinary output and urinary sodium
excretion and has no effect on urinary potassium excretion
