This study examined the impact of menstrual phase, oral contraceptive use and post-menopausal status (collectively referred to as reproductive states) during time of injury on female post-concussion outcomes during the acute phase of recovery. A total of 83 female participants (ages 17 - 71) recruited from a concussion clinic at a rehabilitation hospital were included in the analysis. Personal health information and Rivermead Post-Concussion Questionnaire (RPCQ) scores were collected. Descriptive, bivariate regression and multivariable regression models were performed. The reproductive states were not associated with RPCQ scores during the first week of recovery; however, females taking oral contraceptives had significantly higher RPCQ scores two weeks post-injury. The other reproductive states do not appear related to RPCQ scores up to 2 weeks post injury. Being on birth control was independently associated with more symptomatology.M.Sc
