Background: Acute disseminated encephalomyelitis (ADEM) is rare,
monophasic, demyelinating disease of the CNS which sometimes could be
refractory to traditional treatment. Case Presentation: We present a
case of fulminant ADEM which is treated with combination of
corticosteroid, intravenous immunoglobulin and cyclosporine.
Conclusion: Immunosuppressive agents such as cyclosporine may be
effective especially in fulminant form of the disease
