Bioactive glass particulate has been applied to dentistry in the
treatment of bone defects, ridge preservation and periodontal bone
defects including the furcation defects. The aim of this study was to
compare the clinical attachment gain and vertical and horizontal bone
fill obtained with open flap debridement (OFD) alone and OFD with
bioactive glass particulate in the treatment of mandibular Class II
furcation defects. Twenty mandibular class II furcation defects were
selected in 16 systemically healthy patients out of which 10 defects
were treated with OFD alone (Group I) and other 10 defects were treated
with OFD and bioactive glass particulate (Group II). Each defect was
randomly assigned to Group I and Group II. The soft tissue and hard
tissue measurements including vertical probing depth, horizontal
probing depth, clinical attachment level, gingival recession, vertical
depth of the furcation defects, and horizontal depth of the furcation
defects were recorded at baseline and six months post surgery. At 6
months evaluation, both treatment procedures resulted in significant
improvement in soft tissue and hard tissue parameters when compared to
the baseline. There was no significant difference between the two
groups with respect to soft tissue changes (p>0.05) like probing
depth reduction (3.30 mm versus 2.90 mm), clinical attachment level
gain (2.90 mm Vs 2.80 mm) and gingival recession. Vertical defect fill
were significantly greater in the bioactive glass sites (1.50 mm)
compared to control sites (0.80 mm). There was highly significant
reduction in horizontal probing depth of the defect (1.80 mm Vs 1.10
mm, p< 0.05) after 6 months post surgery. In conclusion, bioactive
glass showed significant improvement in clinical parameters like
vertical and horizontal defect fill in mandibular class II furcation
defects when compared to OFD