Medknow Publications on behalf of the Neurological Society of India
Abstract
The field of myology has undergone remarkable changes. From the period
of early clinical descriptions and clinical classifications, new
knowledge of these disorders has come from the developments of
histopathology, enzyme histochemistry and later, immunocytochemistry
and electron microscopy. These techniques have enhanced the
understanding of the pathophysiology of myopathies at the cellular
level. The parallel evolution of molecular genetics has taken the
science further not only by way of understanding and accuracy of
diagnosis, but has opened up exciting possibilities of modulation of
these chronic debilitating diseases. This review gives a personal
perspective of the developments in the field of myology