Objectives: Diabetes mellitus is associated with a greater likelihood
of developing certain oral mucosal disorders. This study was aimed at
assessing the prevalence of oral mucosal lesions (OMLs) in patients
with type 2 diabetes (DM2) and to investigate the association of such
lesions with metabolic control of the disease. Methods: This
cross-sectional study involved 391 patients with DM2 and 391
non-diabetic control subjects. Demographic information and data on the
duration and type of diabetes, glycosylated hemoglobin (HbA1c) values,
medical history, and current use of medication were obtained from
medical records. Detailed oral examination was performed in accordance
with international criteria. Results: The prevalence of OMLs was
significantly higher among diabetic patients (45.5%) than among control
subjects (38.4%) (P = 0.042). Patients with diabetes had a higher
prevalence of geographic tongue (GT) (P = 0.017), denture stomatitis (P
= 0.018), and angular cheilitis (P = 0.006) than controls. Overall,
diabetic patients with poor metabolic control had a significantly
higher prevalence of OMLs and xerostomia than patients with moderately
and well-controlled disease (P < 0.05). Conclusions: The prevalence
of OMLs was significantly higher in diabetic patients than in control
subjects. Higher occurrence of OMLs was significantly associated with
poor metabolic control
