Anti-inflammatory and Antipyretic Activities of Panicum Maximum

Abstract

Anti-inflammatory and antipyretic activities of leaf extract of Panicum maximum were evaluated to ascertain the folkloric claim of its use in fevers and inflammatory conditions. The crude leaf extract (48 – 144 mg/kg) of Panicum maximum was investigated for anti-inflammatory and antipyretic activities using various experimental models. The extract caused a significant (p<0.05 – 0.001) dose-dependent reduction in inflammation and fever induced by different agents used. The anti-inflammatory and antipyretic effects of this plant may in part be mediated through the secondary metabolites present in the plant

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