Chrysophyllum albidum is a common plant in the tropical Central, East
and West Africa region.Its fruits are widely consumed and plant parts
are vastly utilized. The broad utilization and consumption of this
plant parts make it pertinent to examine its effect on blood
parameters. This study was therefore designed to investigate the effect
of methanolic extract of Chrysophyllum albidum on haematological
indices in mice. Seventy five Swiss albino male mice (19g β 22g)
were used for this study. 45 of which were anaesthetized with diethyl
ether and 0.25mls (40%) of their blood drained through the
retro-orbital plexus. Haemoglobin concentration (Hb) was determined
24hours after. Animals with Hb of <11.12 g/dl were considered
anaemic and randomly divided into five groups of fifteen animals.
Group1 - control animals (Nor), Group 2 - animals treated with
1000mg/kg b.w of Chrysophyllum albidumalone (MeCaB), Group 3- animals
bled and treated with ferrous sulphate (BHaem), Group 4 - animals bled
and treated with MeCaB (BMeCaB) and Group 5 animals were bled and
untreated (Bla). Complete blood count was done using standard methods
on days 3 and 7.The body weight of BMeCaB group showed significant
(p<0.05) increase compared with control and Bla. The BMeCaB group
showed significant increase (p<0.05) in RBC and Packed Cell Volume
within 48 hours of treatment and up to day 7 compared with Bla and
BHaem. There was significant decrease (p<0.05) in the Neutrophil
lymphocyte ratio of BMeCaB and MeCaB compared with Bla.This study
established the haematinic potentials of Chrysophyllum albidu