Medknow Publications and Staff Society of Seth GS Medical College and KEM Hospital, Mumbai, India
Doi
Abstract
Context: Fournier′s gangrene (FG) is a rapidly progressing acute
gangrenous infection of the anorectal and urogenital area. Aims: The
objectives of this study were to investigate patients with FG and to
determine risk factors that affect mortality. Settings and Design:
Retrospective clinical study. Materials and Methods: Clinical
presentations and outcomes of surgical treatments were evaluated in 68
patients with FG. Statistical Analysis Used: Chi-square,
Student′s t -test, and logistic regression test. Results: Mean
age of patients was 54 and female-to-male ratio was 9:59. Among the
predisposing factors, diabetes mellitus (DM) was the most common ( n
=24, 35.3%), and sepsis on admission was detected in 31 (45.6%) and 15
(22.1%) patients, respectively. Seven (10.3%) patients died. Using
logistic regression test, Fournier′s Gangrene Severity Index
(FGSI)> 9, DM and sepsis on admission were found as prognostic
factors. Conclusions: FG has a high mortality rate, especially in
patients with DM and sepsis. An FGSI value> 9 indicates high
mortality rate
