In 5-10% of cases of brucellosis may lead to central nervous system
manifestation presenting most often as a meningitis or
meningoencephalitis. We report three neurobrucellosis who have
different presentation. First patient; a 49-year-old-woman who
developed diffuse cerebral white matter lesions as leukoencephalopathy
associated with neurobrucellosis, presented with gait disturbance,
behavior change and seizure. Second patient; 44-year-old man was
admitted to our hospital with a complaint of progressive motor weakness
in his bilateral legs for four months and headache for one year. The
patient’s symptoms may be explained with myeloradiculopathy and
meningoencephalitis but the clinical picture didn’t correlate
with imaging findings. Third patient; 23-year-old man was admitted to
our hospital with a complaint of transient numbness attacks in his left
of face and hand and headache for twenty days. He presented as
meningitis which is the most clinical presentation of neurobrucellosis
and meningovascular complications. Conclusively, brucellosis is still
endemic in Turkey and thus neurobrucellosis should be considered in the
unexplained neurological symptoms such as cognitive dysfunction, young
transient ischemic attacks, paraparesis and psychiatric symptoms