Medknow Publications on behalf of The Indian Association of Dermatologists, Venereologists and Leprologists (IADVL)
Abstract
Acrokeratosis paraneoplastica of Bazex is rare condition, characterized
with scaly hyperkeratotic psoriasiform plaques on acral parts of body
(helices, nose, and malar and acral surfaces), and in later stages
propagation to the limbs and trunk.This syndrome is distinct marker for
different neoplastic conditions, predominantly squamous cell carcinoma
of the upper aerodigestive tract with possible cervical lymph node
metastases.In this paper we present 56 years old male patient, with
hyperkeratotic plaques on the skin of his palms, soles, ear lobes and
apex of the nose. Detailed examination found tumorous swelling on the
left side of his neck. Histopathologic examination revealed solid
anaplastic metastatic tumor. Patient died before primary tumor could be
found. Bazex syndrome can appear before the diagnosis of internal
malignancies, and thus is important for dermatologists to recognize it
in favor of early diagnosis of specific malignant process