Medknow Publications on behalf of the Association of Radiation Oncologists of India (AROI)
Abstract
Primary plasmacytoma of the gastrointestinal tract is a rare entity. We
report a case of a primary gastric plasmacytoma in a 57-year-old man
who presented with upper-gastrointestinal bleeding. Endoscopy showed a
nodular gastric mass with central umblication. Histological examination
of the gastrectomy specimen revealed a monoclonal lambda-chain
extramedullary plasmacytoma. Further staging was found to be negative
for multiple myeloma. As other more common pathologic processes at this
site may also be endowed with numerous plasma cells, awareness of this
entity and distinction using immunohistochemistry are extremely
crucial. Because systemic disease ultimately develops in many patients
with localized plasmacytoma, such patients should be followed closely
for the appearance of clinical, biochemical, and roentgenologic
evidence of multiple myeloma