Biotransformations are becoming increasingly popular in the production
of enantio- and regiopure- intermediates for synthesis of complex
organic compounds. Whole microbial cells or enzymes can be used to
carry out such specific chemical reactions that are otherwise difficult
to achieve synthetically. Chemoenzymatic synthesis is of particular
interest in the pharmaceutical industry where some steps can be carried
out enzymatically to obtain chiral synthons for further
enzymatic/chemical processing. In this report, we discuss some recent
developments in the field together with a few examples