Medknow Publications on behalf of Association of Surgeons of India
Abstract
A 45-year-old lady presented with history of painless bleeding per
rectum for 2 months. Colonoscopy revealed a small growth involving the
region of the anorectal junction, biopsy of which was reported to be
poorly differentiated carcinoma, with the possibility of amelanotic
melanoma. At the time of undergoing abdominoperineal resection the
patient did not show any obvious evidence of regional lymph node
involvement or distant metastases. Histopathology of the tumour after
routine haematoxylin and eosin (H&E) stain and subsequent special
staining with anti-melanoma antibodies, HMB 45 and S 100, conclusively
proved amelanotic melanoma. She developed multiple secondary deposits
in the liver after 3 months of surgery and a recent bone scan revealed
multiple metastases in the bones. However, she is still alive at the
time of reporting
