Medknow Publications on behalf of Indian Society of Human Genetics
Abstract
Genetic markers are used for identity testing and paternity analysis
depends on knowing the allele frequencies in the population.
Minisatellites show allelic variability in the number of repeat units.
We have studied the allele frequencies and heterozygosity of two VNTRs
(ApoB and D1S80) in Iranian populations. A total of 96 and 82
chromosomes were analyzed by PCR and gel electrophoresis for ApoB and
D1S80 respectively. In the ApoB system, allele 37 was the most common
followed by allele 35 whereas allele 23 was the most common followed by
allele18 at the D1S80 locus. Observed heterozygosity was relatively low
in ApoB than D1S80 locus, however, no significant differences were
found between observed and expected heterozygosity