Understanding, controlling and manipulation of patient data as well as shape, geometry and structure of the biomedical objects are important for developing Biomedical Engineering (BME) applications. Medical Reverse Engineering (MRE) is aimed to use the Reverse Engineering (RE) technology to reconstruct 3D models of the anatomical structures and biomedical objects for design and manufacturing of medical products as well as BME research and development. This paper presents the state of the art applications and methods about MRE. Different concepts and methodologies are provided to understand fundamentally the MRE processes and workflow. The key MRE applications are presented, including personalised implants for bone reconstruction, dental implants and simulations, surgical tools, medical training, vision science and optometry, orthopedics, ergonomics, orthosis, prosthesis, and tissue engineering. The current challenges as well as the hardware and software for MRE application development and research are discussed
