This paper uses material on the careers of chemists in the twentieth century from the ‘Studies of the British Chemical Community, 1880-1970’ project to place the experiences of chemists in the context of this dynamic new research area. The paper highlights the way that the values associated with a traditional professional ‘ideal type’ of the independent practitioner were retained despite a marked shift to salaried employment during the twentieth century. Career mobility amongst chemists was underpinned by these values and by the transferability of their core skills