We examine Bisphenol-A (BPA) as a case that illustrates key challenges in addressing the public health risks of consumer products in the 21st century. First, we trace growing concerns about the effects of BPA on human health, showing how regulatory approaches can exacerbate the difficulty of dealing with the unforeseen risks of chemicals in consumer products. Second, we highlight the question of who should bear the responsibility – and the cost – of rectifying or preventing unforeseen chemical risks in consumer products. Third, we discuss the challenge of substituting out a potentially hazardous chemical from consumer products in the context of well established global production chains and consumption patterns. Utilitarian and deontological ethical frameworks have influenced societal debates surrounding each of these three challenges, creating moral dilemmas for actors with different forms of moral agency – both those implicated in the production of harmful chemicals and those pursuing remedies