For several decades psychotherapy research has tried to find what works in therapy, in order to increase the efficiency of psychotherapy. Through this research, the therapeutic relationship has emerged as one of the leading curative factors. This paper seeks so elucidate what factors in the therapeutic relationship that contribute to this curative effect. By reviewing the literature pertaining to the topic, the author shows that a multitude of factors are related to outcome. Some of these are therapist variables, such as warmth, empathy, and emotional well being. Client variables such as reactance, locus of control, attachment style, and severity of disorder. Rogerian facilitative conditions, i.e. positive regard, congruence, and empathy. Finally the working alliance, trough affective bond, agreement on task and goal, is also shown to be related to the outcome. The paper sums up several guidelines that might improve the therapeutic relationship, and thus improving the chances of a successful therapy