This paper presents a Personalized Healthcare System (PHS), a decision support tool that can adapt to changing conditions, such as aging and illness, in individual patients. The system consists of three components: a unique personalised profile, a collection of web based tools and a web based repository for managing interactions between clinicians and tools. The proposed system makes extensive use of software agents, both for collecting the initial information required to construct a personalized profile and for transporting the information needed to use the on-line decision support tools. The paper discusses the operation of a PHS and suggests possible implementation issues
