Differences in urinary excretion of monochlorobenzene between rats and humans were studied. Monochlorobenzene was administered to rats and humans intraperitoneally, orally or by inhalation. Urinary p-chlorophenylmercapturic acid and 4-chlorocatechol, after hydrolysis of its conjugate, were measured. The excretion of p-chlorophenylmercapturic acid was somewhat more than that of 4-chlorocatechol in rats which were administered monochlorobenzene orally or intraperitoneally. The excretion of p-chlorophenylmercapturic acid was markedly less than that of 4-chlorocatechol in humans who received monochlorobenzene orally or by inhalation. The results indicate that the 4-chlorocatechol conjugate is a suitable index of metabolites in the urine of workers exposed to monochlorobenzene.</p

Eaton, Charles

Kessar, Radha

Kulshammer, Burkhard

Sambale, Benjamin

arXiv

Ogata, Masana

Shimada, Yoshihiro

Okayama University Digital Information Repository

Differences in urinary monochlorobenzene metabolites between rats and humans.

We give a classification, up to Morita equivalence, of 2-blocks of quasi-simple groups with abelian defect groups. As a consequence, we show that DonovanÊ¼s conjecture holds for elementary abelian 2-groups, and that the entries of the Cartan matrices are bounded in terms of the defect for arbitrary abelian 2-groups. We also show that a block with defect groups of the form C2mÃ—C2mC2mÃ—C2m for mâ©¾2mâ©¾2 has one of two Morita equivalence types and hence is Morita equivalent to the Brauer correspondent block of the normaliser of a defect group. This completes the analysis of the Morita equivalence types of 2-blocks with abelian defect groups of rank 2, from which we conclude that DonovanÊ¼s conjecture holds for such 2-groups. A further application is the completion of the determination of the number of irreducible characters in a block with abelian defect groups of order 16. The proof uses the classification of finite simple groups

The University of Manchester - Institutional Repository

English

2-blocks with abelian defect groups

We give a classification, up to Morita equivalence, of 2-blocks of quasi-simple groups with abelian defect groups. As a consequence, we show that Donovanʼs conjecture holds for elementary abelian 2-groups, and that the entries of the Cartan matrices are bounded in terms of the defect for arbitrary abelian 2-groups. We also show that a block with defect groups of the form C2m×C2m for m⩾2 has one of two Morita equivalence types and hence is Morita equivalent to the Brauer correspondent block of the normaliser of a defect group. This completes the analysis of the Morita equivalence types of 2-blocks with abelian defect groups of rank 2, from which we conclude that Donovanʼs conjecture holds for such 2-groups. A further application is the completion of the determination of the number of irreducible characters in a block with abelian defect groups of order 16. The proof uses the classification of finite simple groups

Eaton, C.W.

Kessar, R.

Kuelshammer, B.

Sambale, B.

City Research Online

Okayama University Scientific Achievement Repository

Acta Medica OkayamaVolume 36, Issue 6 1982 Article 10DECEMBER 1982Differences in urinary monochlorobenzenemetabolites between rats and humans.Masana Ogata∗ Yoshihiro Shimada†∗Okayama University,†Okayama University,Copyright c©1999 OKAYAMA UNIVERSITY MEDICAL SCHOOL. All rights reserved.Differences in urinary monochlorobenzenemetabolites between rats and humans.∗Masana Ogata and Yoshihiro ShimadaAbstractDifferences in urinary excretion of monochlorobenzene between rats and humans were stud-ied. Monochlorobenzene was administered to rats and humans intraperitoneally, orally or by in-halation. Urinary p-chlorophenylmercapturic acid and 4-chlorocatechol, after hydrolysis of itsconjugate, were measured. The excretion of p-chlorophenylmercapturic acid was somewhat morethan that of 4-chlorocatechol in rats which were administered monochlorobenzene orally or in-traperitoneally. The excretion of p-chlorophenylmercapturic acid was markedly less than that of4-chlorocatechol in humans who received monochlorobenzene orally or by inhalation. The re-sults indicate that the 4-chlorocatechol conjugate is a suitable index of metabolites in the urine ofworkers exposed to monochlorobenzene.KEYWORDS:monochlorobenzene, species-difference, mercapturic acid, 4-chlorocatedchol, uri-nary metabolites∗PMID: 7158430 [PubMed - indexed for MEDLINE]Copyright (C) OKAYAMA UNIVERSITY MEDICAL SCHOOL1Ogata and Shimada: Differences in urinary monochlorobenzene metabolitesProduced by The Berkeley Electronic Press, 19822Acta Medica Okayama, Vol. 36 [1982], Iss. 6, Art. 10http://escholarship.lib.okayama-u.ac.jp/amo/vol36/iss6/103Ogata and Shimada: Differences in urinary monochlorobenzene metabolitesProduced by The Berkeley Electronic Press, 19824Acta Medica Okayama, Vol. 36 [1982], Iss. 6, Art. 10http://escholarship.lib.okayama-u.ac.jp/amo/vol36/iss6/10

Charles W. Eaton

Radha Kessar

Burkhard Külshammer

Benjamin Sambale

Crossref

Advances in Mathematics

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Differences in urinary monochlorobenzene metabolites between rats and humans.

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