This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the Process Intensification Network, the Institution of Mechanical Engineers, the Heat Transfer Society, HEXAG - the Heat Exchange Action Group, and the Energy Institute, ASME Press, LCN London Centre for Nanotechnology, UCL University College London, UCL Engineering, the International NanoScience Community, www.nanopaprika.eu.We report on a new class of integrated optofluidic devices, fabricated by femtosecond laser
micromachining. The capability to combine optical waveguides with microfluidic channels in the same
glass chip provides a very powerful platform, introducing new tools in the field of optical sensing. Two
recent applications that greatly benefitted from this novel technology are on-chip optical manipulation of
single cells by optical forces and optical sensing of the refractive index of fluids by quantum states of light.
The specific properties of robustness, alignment free and portability of these devices pave the way to the use
of these advanced sensing technologies outside the lab, in a real application environment
