The improvement of vascular health in the exercising limb can be attained by sprint interval training (SIT).
However, the effects on systemic vascular function and on circulating angiogenic cells (CACs) which may contribute to endothelial repair have not been investigated. Additionally, a comparison between SIT and sprint continuous training (SCT) which is less time committing has not been made

A Yamashina

A Zampetaki

B Takase

BJ Whipp

C Goto

C Schmidt-Lucke

DH Walter

DHJ Thijssen

DJ Green

Emma Harris

G Morici

GF Mitchell

GH Simmons

GK Birk

GP Fadini

H Tanaka

HB Rossiter

J George

J Hur

J Myers

J Rehman

JA Laukkanen

JR Crosby

KA Burgomaster

Karen M. Birch

KD Currie

KM Naseem

LJ Whyte

M Cocks

M Rakobowchuk

M Sandri

M Vasa

Mark Rakobowchuk

MC Corretti

MF O'Rourke

MH Laughlin

MJ Gibala

MJ Kuchan

N Dusserre

NT Jenkins

OD McEleavy

P Sarto

PCG Simons

Q Shi

R Hambrecht

R Ross

RM Cubbon

S Steiner

SN Doshi

T Neunteufl

Tim Lahm

TM Tinken

U Laufs

U Wisloff

WL Beaver

YC Boo

YC Chiu

PLoS ONE

English

PubMed

Introduction: The improvement of vascular health in the exercising limb can be attained by sprint interval training (SIT). However, the effects on systemic vascular function and on circulating angiogenic cells (CACs) which may contribute to endothelial repair have not been investigated. Additionally, a comparison between SIT and sprint continuous training (SCT) which is less time committing has not been made. Methods: 12 women (22±2 yrs) completed 12 sessions of either SIT (n = 6) or work-matched SCT (n = 6) on 3 days/week. Pre and post-training assessments included brachial artery endothelial function and peripheral blood analysis for CAC number (CD34+/CD34+CD45dim). CAC function was measured by migration and adhesion assays. Cardio-respiratory fitness, carotid arterial stiffness and carotid-radial and brachial-foot pulse wave velocity (PWV) were also evaluated. Results: CD34+ CACs increased following training in both groups but CD34+CD45dim did not (Pre CD34+: 40±21/105 leukocytes, Post CD34+: 56±24/105 leukocytes, main time effect p0.05). Discussion: SCT involving little time commitment is comparable to SIT in increasing CD34+ cell number and [Formula: see text]. An increased mobilisation of CD34+ CACs suggests that sprint training may be an effective method to enhance vascular repair

Harris, E

Rakobowchuk, M

Birch, KM

White Rose Research Online

Sprint interval and sprint continuous training increases circulating CD34+ cells and cardio-respiratory fitness in young healthy women.

The improvement of vascular health in the exercising limb can be attained by sprint interval training (SIT). However, the effects on systemic vascular function and on circulating angiogenic cells (CACs) which may contribute to endothelial repair have not been investigated. Additionally, a comparison between SIT and sprint continuous training (SCT) which is less time committing has not been made.12 women (22±2 yrs) completed 12 sessions of either SIT (n = 6) or work-matched SCT (n = 6) on 3 days/week. Pre and post-training assessments included brachial artery endothelial function and peripheral blood analysis for CAC number (CD34+/CD34+CD45dim). CAC function was measured by migration and adhesion assays. Cardio-respiratory fitness, carotid arterial stiffness and carotid-radial and brachial-foot pulse wave velocity (PWV) were also evaluated.CD34+ CACs increased following training in both groups but CD34+CD45dim did not (Pre CD34+: 40±21/105 leukocytes, Post CD34+: 56±24/105 leukocytes, main time effect p0.05).SCT involving little time commitment is comparable to SIT in increasing CD34+ cell number and [Formula: see text]. An increased mobilisation of CD34+ CACs suggests that sprint training may be an effective method to enhance vascular repair

Karen M Birch

Directory of Open Access Journals

Brunel University Research Archive

Sprint interval and sprint continuous training increases circulating CD34+ cells and cardio-respiratory fitness in young healthy women

Crossref

Sprint Interval and Sprint Continuous Training Increases Circulating CD34+ Cells and Cardio-Respiratory Fitness in Young Healthy Women

Introduction: The improvement of vascular health in the exercising limb can be attained by sprint interval training (SIT). However, the effects on systemic vascular function and on circulating angiogenic cells (CACs) which may contribute to endothelial repair have not been investigated. Additionally, a comparison between SIT and sprint continuous training (SCT) which is less time committing has not been made.

Methods: 12 women (2262 yrs) completed 12 sessions of either SIT (n = 6) or work-matched SCT (n = 6) on 3 days/week. Pre and post-training assessments included brachial artery endothelial function and peripheral blood analysis for CAC number (CD34+/CD34+CD45dim). CAC function was measured by migration and adhesion assays. Cardio-respiratory fitness, carotid arterial stiffness and carotid-radial and brachial-foot pulse wave velocity (PWV) were also evaluated. 

Results: CD34+ CACs increased following training in both groups but CD34+CD45dim did not (Pre CD34+: 40621/105 leukocytes, Post CD34+: 56624/105 leukocytes, main time effect p,0.05). Brachial artery flow-mediated dilation (FMD) increased following SIT but SCT had no effect (Pre SIT: 5.063.4%, Post SIT: 5.963.0%, Pre SCT: 7.262.7%, Post SCT: 6.562.9%; group x time interaction p = 0.08). VO_ 2max increased in both training groups (Pre: 34.664.6 mlNkgNml21, Post:36.965.4 ml/kg/ml, main time effect p,0.05). CAC function, carotid arterial stiffness and PWV did not change after training (p.0.05).

Discussion: SCT involving little time commitment is comparable to SIT in increasing CD34+ cell number and VO_ 2max. An increased mobilisation of CD34+ CACs suggests that sprint training may be an effective method to enhance vascular repair

Harris, Emma

Rakobowchuk, Mark

Birch, Karen M.

University of Huddersfield Repository

The improvement of vascular health in the exercising limb can be attained by sprint interval training (SIT). However, the effects on systemic vascular function and on circulating angiogenic cells (CACs) which may contribute to endothelial repair have not been investigated. Additionally, a comparison between SIT and sprint continuous training (SCT) which is less time committing has not been made.). CAC function was measured by migration and adhesion assays. Cardio-respiratory fitness, carotid arterial stiffness and carotid-radial and brachial-foot pulse wave velocity (PWV) were also evaluated.>0.05). CACs suggests that sprint training may be an effective method to enhance vascular repair

Sprint interval and sprint continuous training increases circulating CD34+ cells and cardio-respiratory fitness in young healthy women

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Directory of Open Access Journals

Brunel University Research Archive

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