Burdío, J. M.

Castiella, T.

García-Hernández, L.

Gracia-Llanes, J.

Güemes, A.

Hernáez, A.

Iruzubieta, P.

Junquera, M. C.

Lucía, O.

López-Alonso, B.

Mejía, E.

Naval, A.

Sarnago, H.

English

Repositorio Universidad de Zaragoza

ELECTRON MICROSCOPE EVALUATION OF IRREVERSIBLE ELECTROPORATION ON THE LIVER IN A PORCINE MODEL  Mª Concepción Junquera1, Tomás Castiella2,Javier Gracia-LLanes1, Borja López-Alonso3, Alba Hernáez4, Lara García-Hernández3, Antonio Güemes4, Elaine Mejia2, Pablo Iruzubieta1, Alejandro Naval3, Hector Sarnago3, Oscar Lucia3, Jose M. Burdio3  1 Faculty of Medicine, Department of Human Anatomy and  Histology, University of Zaragoza  / Institute for Health Research Aragón (IIS), Domingo Miral s/n, 50009 Zaragoza, Spain. 2 Faculty of Medicine, Department of Pathology, Hospital Clínico Universitario Lozano Blesa, Zaragoza, Spain / Institute for Health Research Aragón (IIS), Domingo Miral s/n, 50009 Zaragoza, Spain. 3 Department of Electronic Engineering and Communications. Group of Power Electronics and Microelectronics 4 Department of Surgery Hospital Clínico Universitario Lozano  Blesa, Zaragoza, Spain Institute for Health Research Aragón (IIS), Domingo Miral s/n, 50009 Zaragoza, Spain.   Introduction: &MM@Q@MND=G@ @G@>OMJKJM<ODJI &/" DIQJGQ@N <KKGD><ODJI JA @G@>OMD> AD@G? KPGN@N OJ>@GGN G@<?DIB OJ DI?P>@? K@MH<I@IO I<IJKJM@N JI OC@ KG<NH< H@H=M<I@ KMJQD?DIB < IJIOC@MH<G >@GG ?@<OC 1C@KMJKJN@?H@>C<IDNHNJA <KJKOJOD> JM I@>MJOD> >@GG ?@<OC ?P@ OJ &/"DI>GP?@?DNMPKODJIJA>@GGH@H=M<I@><PN@?=TKJM@@SK<INDJI<I?JNHJOD>JM>C@HD><GNOM@NN&IM@>@IOT@<MN&/"C<N@H@MB@?<N<I@RH@OCJ?JAOPHJM<=G<ODJI&I<??DODJI&/"C<N=@@IRD?@GT O@NO@? <I?K@M AJMH@? DI N@Q@M<G JMB<IN <I? OPHJMN !@NKDO@ OC@N@ KMJHDNDIB?@Q@GJKH@ION OC@ API?<H@IO<G H@>C<IDNHN G@<?DIB OJ >@GG ?@<OC M@H<DI PIFIJRI &I OCDNPGOM<NOMP>OPM<GNOP?TOCJN@HJ?DAD><ODJINAMJH>@GG?@<OCOJM@B@I@M<ODJIJ>>PMMDIBDI?DAA@M@IO>@GGPG<M OTK@N AJMHDIB API>ODJI<G C@K<OD> PIDO <M@ <NN@NN@? =T PNDIB KJM>DI@ GDQ@MN PI?@M?DAA@M@IO@SK@MDH@IO<G>JI?DODJIN Material and methods: &IOCDNNOP?TKDBNFBR@M@OM@<O@?PNDIBK<M<GG@GKG<O@@G@>OMJ?@NN@K<M<O@? =T OC@RD?OC JA OC@ GDQ@M D@  >H <I?<KKGTDIB KPGN@N JAhNRDOC <AM@LP@I>TJA%UOJ<QJD?OC@MH<G?<H<B@1CM@@@G@>OMD>AD@G?DIO@INDOD@NR@M@O@NO@?JI@DI@<>C JA OC@ OCM@@ PN@? GDQ@M GJ=PG@N 3>H 3>H <I? 3>H-JNOJK@M<ODQ@=DJKND@N R@M@ K@MAJMH@? <O C  <I?  ?<TN <AO@M OC@ NODHPG<ODJI 0<HKG@N R@M@ MJPODI@GTKMJ>@NN@?AJMOM<INHDNNDJI<I?N><IIDIB@G@>OMJIHD>MJN>JKTQDNP<GDU<ODJI Results:1CM@@CJPMN<AO@M &/"<KKGD><ODJI<GO@M<ODJINJA>@GGH@H=M<I@DIOC@@G@>OMJKJM<O@?<M@<R@M@J=N@MQ@?1C@TM<IB@? AMJHI<IJH@OMD>KJM@N OJRD?@?DNMPKODJIRDOCNKM@<?DIBJAJMB<I@GG@N DI OC@ @SOM<>@GGPG<M NK<>@  @GGPG<M EPI>ODJIN =@OR@@I C@K<OJ>TO@N R@M@ IJOH<DIO<DI@? !DG<O@? BM<IPG<M @I?JKG<NHD> M@OD>PGPH <I? HDOJ>CJI?MD< R@M@ J=N@MQ@?POJKC<BD> KMJ>@NN@N DIDOD<O@? NDI>@ KM@N@I>@ JA <POJKC<BJGTNJNJH@N R<N @QD?@I>@?0PMKMDNDIBGT (PKAA@M <N R@GG <N &OJ >@GGN @MTOCMJ>TO@N <I? I@POMJKCDGN NCJR@? >JIN@MQ@?H@H=M<I@N #@I@NOM<O@? @I?JOC@GD< JA !DNN@ NK<>@ <GNJ NCJR@? DIO<>O H@H=M<I@N 1CM@@?<TN<AO@M &/"<KKGD><ODJINJH@C@K<OJ>TO@NNCJR@?IP>G@<M AM<BH@IO<ODJIRDOCJPO?DNMPKODJIJA >@GG H@H=M<I@ NPBB@NODIB <KJKOJNDN %JR@Q@M OC@ HJNO JA OC@N@ C@K<OD> >@GGN NCJR@?I@>MJNDN =@DIB OC@I M@HJQ@? =T H<>MJKC<B@N 0P=N@LP@IO >C<IB@N ?@HJINOM<ODIB OC@=@BDIIDIBJAM@B@I@M<ODJIJAC@K<OJ>TO@N<I?de novo Q<N>PG<M AJMH<ODJIR@M@AJPI?Conclusion: "SK@MDH@IO<G ?<O< NCJR@? OC<O PGOM<NOMP>OPM<G NOP?T DN <I DI?DNK@IN<=G@ OJJG AJMM@GD<=G@<NN@NNH@IOJA&/"<=G<ODJI Acknowledgements:POCJMNRJPG?GDF@OJ<>FIJRG@?B@OC@PN@JAServicio General de Apoyo a la Investigación-SAI2IDQ@MND?<??@7<M<BJU<125P-HP 90

Electron microscope evaluation of irreversible electroporation on the liver in a porcine model

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Electron microscope evaluation of irreversible electroporation on the liver in a porcine model

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